| Score | Rank | Name | Followers | Following | Country | ||
|---|---|---|---|---|---|---|---|
| 01 |  |  | Donald J. Trump @realDonaldTrump | 87.3M | 51 | Former President USA | |
| 02 |  |  | Joe Biden @JoeBiden | 37.1M | 47 | President USA | |
| 03 |  |  | Kamala Harris @KamalaHarris | 20M | 728 | Vice President USA | |
| 04 |  | Jair Bolsonaro @jairbolsonaro | 11.1M | 487 | Former President Brazil | ||
| 05 |  | Andrés Manuel López Obrador @lopezobrador_ | 9.7M | 292 | President Mexico | ||
| 06 |  | Luiz Inácio Lula da Silva @LulaOficial | 7.5M | 2.9K | President Brazil | ||
| 07 |  | Gustavo Petro @petrogustavo | 6.6M | 2.7K | President Colombia | ||
| 08 |  | Justine Trudeau @JustinTrudeau | 6.4M | 919 | Prime Minister Canada | ||
| 09 |  | Nayib Bukele @nayibbukele | 5M | 589 | President El Salvador | ||
| 10 |  | Nicolás Maduro @NicolasMaduro | 4.4M | 120 | President Vanezuela | ||
| 11 |  | Iván Duque Márquez @IvanDuque | 2.5M | 1.7K | President Colombia | ||
| 12 |  | Sebastián Piñera @sebastianpinera | 2.4M | 19K | President Chile | ||
| 13 |  | Guillermo Lasso @LassoGuillermo | 1.3M | 1.4K | President Ecuador | ||
| 14 |  | Martín Vizcarra @MartinVizcarraC | 1.3M | 480 | President Peru | ||
| 15 |  | Lenin Moreno @Lenin | 1M | 41 | Former President Ecuador | ||
| 16 |  | Luis Abinader @luisabinader | 965K | 5.2K | President Dominican Republic | ||
| 17 |  | Miguel Díaz-Canel @DiazCanelB | 746K | 230 | President Cuba | ||
| 18 |  | Mario Abdo Benítez @MaritoAbdo | 700K | 326 | President Paraguay | ||
| 19 |  | Juan Orlando Hernández @JuanOrlandoH | 460K | 1.1K | President Hondurus | ||
| 20 |  | Jovenel Moïse @moisejovenel | 457K | 0 | President Haiti |
