| Score | Rank | Name | Followers | Following | Category | ||
|---|---|---|---|---|---|---|---|
| 01 |  |  | Imran Khan @ImranKhanPTI | 18.4M | 0 | Politician | |
| 02 |  |  | Asad Umar @Asad_Umar | 9.1M | 4 | Politician | |
| 03 |  |  | Maryam Nawaz Sharif @MaryamNSharif | 7.8M | 12.5K | Politician | |
| 04 |  | Sheikh Rashid Ahmad @ShkhRasheed | 7.5M | 2 | Politician | ||
| 05 |  | Shehbaz Sharif @CMShehbaz | 6.4M | 281 | Politician | ||
| 06 |  | Ch Fawad Hussain @fawadchaudhry | 6M | 2825 | Politician | ||
| 07 |  | Bilawal Bhutto Zardari @BBhuttoZardari | 5M | 2545 | Politician | ||
| 08 |  | Shah Mahmood Qureshi @SMQureshiPTI | 5M | 17 | Politician | ||
| 09 |  | Murad Saeed @MuradSaeedPTI | 4.5M | 34 | Politician | ||
| 10 |  | Dr. Arif Alvi @ArifAlvi | 4.1M | 152 | Politician | ||
| 11 |  | Jahangir Khan Tareen @JahangirKTareen | 4M | 135 | Politician | ||
| 12 |  | Shafqat Mahmood @Shafqat_Mahmood | 4M | 167 | Politician | ||
| 13 |  | Faisal Javed Khan @FaisalJavedKhan | 3.7M | 1620 | Politician | ||
| 14 |  | Ali Muhammad Khan @Ali_MuhammadPTI | 3.5M | 11 | Politician | ||
| 15 |  | Zartaj Gul Wazir @zartajgulwazir | 3.4M | 219 | Politician | ||
| 16 |  | Khawaja Saad Rafique @KhSaad_Rafique | 3M | 111 | Politician | ||
| 17 |  | Pervez Musharraf @P_Musharraf | 2.6M | 1 | Politician | ||
| 18 |  | Ahsan Iqbal @betterpakistan | 2.6M | 237 | Politician | ||
| 19 |  | Shireen Mazari @ShireenMazari1 | 2.4M | 109 | Politician | ||
| 20 |  | Khawaja M. Asif @KhawajaMAsif | 2.4M | 338 | Politician |
